Programmed necrosis and autophagy in immune function
نویسندگان
چکیده
منابع مشابه
Apoptosis, Autophagy, and Necrosis in Murine Embryonic Gonadal Ridges and Neonatal Ovaries: An Animal Model
Background: In mammalian ovaries, loss of over two-thirds of germ cells happens due to cell death. Nonetheless, the exact mechanism of cell death has yet to be determined. The present basic practical study was designed to detect 3 types of programmed cell death, namely apoptosis, autophagy, and necrosis, in murine embryonic gonadal ridges and neonatal ovaries.Methods: Twenty gonadal ridges and ...
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In contrast to the "programmed" nature of apoptosis and autophagy, necrotic cell death has always been believed to be a random, uncontrolled process that leads to the "accidental" death of the cell. This dogma, however, is being challenged and the concept of necrosis also being "programmed" is gaining ground. In particular, mitochondria appear to play a pivotal role in the mediation of programm...
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ژورنال
عنوان ژورنال: Immunological Reviews
سال: 2012
ISSN: 0105-2896
DOI: 10.1111/j.1600-065x.2012.01147.x